tobacco management Advances in Control Tobacco Control and Education Program

Its 4.5% nicotine, by weight, which I believe translates to 45mg nicotine

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While the precise cellular and network mechanisms that underly nicotine induced seizures are not fully elucidated, the cholinergic nuclei in the brainstem and basal forebrain play key roles in arousal and attention via their effects on cortical tone and modulation of such systems could therefore theoretically affect the seizure threshold

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