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These initial groupings were determined by the research team using knowledge from the literature and findings from the pilot study

So, let's say a patient who smoked on average, one pack per day, started at an age of, let's say, 15, and smoked until the age of 35, then he would have 20 pack years

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If you are trying to quit smoking, nicotine replacement therapy (NRT) is a better choice

Semin Immunopathol 35:123137 Nanki N, Fujita J, Yang Y, Hojo S, Bandoh S, Yamaji Y, Ishida T (2001) Expression of oncofetal fibronectin and syndecan-1 mRNA in 18 human lung cancer cell lines