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However, this research has limitations: It used lower nicotine concentrations than many modern products The study was relatively small and focused on rectal tone specifically It didn't account for higher-strength products like 6mg ZYN pouches Higher-strength products like 6mg or 9mg ZYN pouches contain substantially more nicotine and may produce stronger digestive responses

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Even one cigarette can cause: Temporary spikes in blood pressure Faster heart rate Reduced oxygen supply Tightening of blood vessels Frequent smoking keeps the body under constant stress, contributing to long-term hypertension

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