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In 2024, Wegovy also received FDA approval to reduce the risk of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in adults with established cardiovascular disease and either obesity or overweight

The committee ultimately reached a different recommendation, but the staff analysis remains important because it shows where FDA found the record incomplete

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However, the correlation between PDZK1 and ABCG2 needs to be further investigated