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A subset of 2,454 participants from seven trials were included in the pooled meta-analysis.The researchers found that among those assigned to VLNCs or normal nicotine content cigarettes (NNCs), none of the trials reported increases in the mean number of cigarettes smoked or carbon monoxide (CO) exposure at the end of the intervention

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The CARDIA study, a cohort of young adults at baseline, found no association between menthol cigarette use and cessation at 15-year follow up

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