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Inhibitors of the MDM2/p53 interaction, such as UBX0101 and RG7112 (RO5045337), and inhibition of the de-ubiquitinating ubiquitin-specific peptidase 7 (USP7) increase and stabilize p53 levels and have been investigated for their senolytic effects

However, GLP-1s are increasingly easy to access through telehealth platforms such as Hers, Eden and Ro, which only require online consultations

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doi: 10.1177/1559325819891008 70 PawlikTMKeyomarsiK

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