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If pancreatitis is suspected, discontinue RYBELSUS and initiate appropriate management Diabetic Retinopathy Complications: In a pooled analysis of glycemic control trials with RYBELSUS , patients reported diabetic retinopathy related adverse reactions during the trial (4.2% with RYBELSUS and 3.8% with comparator)

Mild nausea may occur

But for many patients, these medications have led to devastating complications including gastroparesis (stomach paralysis), severe gastrointestinal injury, gallbladder disease, and even pancreatic cancer

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By activating GLP-1 receptors in the brain's appetite centers, semaglutide promotes satiety and reduces food intake

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