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(2022) 18: e10514 Supplementary Information Rights and permissions This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited

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As a novel nuclear factor of activated T cells, cytoplasmic 1 (NFATc1)-specific inhibitor, erianin can effectively block BC-induced pathological osteoclast genesis and decrease bone destruction in MDA-MB-231 breast cancer cell-induced bone loss mice (50)