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(A, B) Relative abundance of differentially abundant bacterial genera in OSCC and healthy buccal site

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Mounting evidence indicates that smoking-induced dysbiosis across the oral, respiratory, and gut microbiota perturbs immunemetabolic balance, thereby contributing to the onset and progression of inflammatory, metabolic, and neoplastic diseases

Wilbert, Johannes (1993) Tobacco and Shamanism in South America ISBN 0-300-05790-3 Burns, Eric

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[63] [64] The most important chemicals causing cancer are those that produce DNA damage since such damage appears to be the primary underlying cause of cancer