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Dozens of tobacco company documents, including confidential memorandums, were obtained as part of the proceedings in the recent lawsuit brought by Antonio Cipollone on behalf of his wife, Rose

Studies in cell culture and in animals have suggested that nicotine and its receptors are involved in dopamine signaling and that nicotine can protect against cell damage in dopamine neurons in these experimental models

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14 Motivational interviewing is also observed to slightly increase quitting rate 15 and may be beneficial in combination with first line pharmacotherapy

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