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In contrast to the relatively consistent beneficial profile of GLP-1RAs in CRC, the role of GCG appears to be more heterogeneous

Beyond weight reduction, these medications improve blood sugar control, reduce cardiovascular event risk, and lower inflammatory markers

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doi: 10.1093/annonc/mdh006 14 RehmanSKHaynesJCollignonEBrownKRWangYNixonAMLet al

10.1073/pnas.2021091118 Proc

It belongs to a novel class of agents known as triple agonists, meaning it simultaneously activates three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors