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As Schedule II substances, they carry risks including side effects, misuse, and physical dependence, which is why medical supervision is required

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Low energy & fatigue Feeling constantly tired, lacking energy, or struggling to stay awake could indicate a B12 shortage

Subgroup analysis was conducted by major risk factors, including sex, age, duration of T2DM, CVD, usage of insulin, HbA1c, hypertension, dyslipidemia, and smoking

Actions: Stimulates bile secretion and improves fat digestion Promotes elimination of excess fluids Detoxifies the liver and supports lymphatic flow Improves skin clarity and overall tone

J Biol Chem (2015) 290(9):5696706