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Shungus next steps revealed just how important small pilot studies funded by organizations like the Solve ME/CFS Initiative (SMCI), the Open Medicine Foundation and the Simmaron Research Foundation can be

A critical gap is that aspartate does not appear to have been tested directly at metabotropic G protein-coupled glutamate receptors (mGluRs) [100]

Consider starting with smaller serving sizes and gradually increasing as tolerance improves

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Overall, the evidence points to GLP-1 receptor agonists as promising adjunctive treatments that can reduce binge eating symptoms and improve related eating behaviors in people living with obesity

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