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People are generally considered to be adults at 18, but the age gets adjusted up or down, depending on the percieved benefits for teenagers and society

E-cigarettes also cause neutrophils to release TNF-, IL-10, and IL-1, which activate the p38 and NF-B signaling pathways, leading to inflammation or apoptosis

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Emerging research indicates that vaping aerosol exposure may: Irritate the nasal and upper airway mucosa , potentially triggering or worsening rhinitis symptoms Introduce flavouring compounds (such as diacetyl and cinnamaldehyde) that can provoke inflammatory responses Alter the nasal microbiome , which may influence immune responses and allergy susceptibility Generate ultrafine particulate matter capable of penetrating deep into respiratory tissues It is important to note that the long-term effects of passive vaping exposure on allergic rhinitis are still being studied