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In her words, it was hell. In my 20s, smoking was an integral part of my identity

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It can cause further damage to lungs, leading to chronic obstructive pulmonary disease (COPD), including bronchitis and emphysema

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The most notable change that we have seen is the behavior and morale of the offenders

This approach is based on the previously described causal chain of events that leads from smoking to disease manifestation [6] and leverages the principles of systems toxicology [15]