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The most common clinical signs are stumbling, uncontrollable urine dribbling, drooling, low body temperature, low blood pressure, and an increased response to stimulation

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Our data showed that there wasnt a significant difference in mental health measures between the groups, suggesting reduced nicotine cigarettes might not have adverse psychological effects on this population. Similar to what prior studies reported, Foulds and team found that groups in the reduced nicotine content group were absorbing lower amounts of nicotine and ingesting lower levels of harmful carcinogens such as the biomarker 4-(methylnitrosamino)-1-(3-pryidyl)-1-butanol), more commonly known as NNAL

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