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Hormone Type Smokers (Serum Levels) Non-Smokers Total Testosterone Normal Normal DHEA Increased DHEAS Increased Androstenedione Increased Estradiol Increased Despite the increased levels of certain hormones, the overall fertility and spermatogenesis processes appear to be somewhat resistant to the detrimental effects of tobacco smoke, although the evidence indicates impaired reproductive functions among smokers [6]

Dautre part, la fume secondaire (encore appele fume passive) est compose de fume de tabac expire et, surtout, de fume produite par le bout incandescent de la cigarette

In addition to secreting TGF-, neutrophils can also produce matrix metalloproteinase-9 (MMP-9) and elastase 32-34 , which can negatively affect the airways, including airway narrowing due to airway remodeling, neutrophil elastase-mediated mucus hypersecretion, increased airway smooth muscle responsiveness, and a rapid decline in lung function 35-37

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