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A dysfunctional hyperimmune response in tandem with macrophage activation could trigger hyperferritinemia, and cytokine storm or cytokine release syndrome (CRS)

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Pathological analysis showed tumor cells with marked nuclear atypia, increased mitotic activity, focal pigment production, and positive expression of melanoma markers SOX-10 and HMB-45 (Fig

This subset of particle projections was subjected to a round of maximum-likelihood-based three dimensional classifications with a pixel size of 2.028 , resulting in one well-defined subsets with 162,932 projections