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Tobacco kills eight million people worldwide each year, mainly in low- and middle-income countries where 80% of the worlds smokers live

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Based on the IC 50 data, the chemicals that were the most toxic from high to low were: ethyl maltol, furaneol, maltol, ethyl vanillin, vanillin, and benzyl alcohol

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[6] The photograph was nominated by Slate in 2011 for a list of "New Classics", products of the culture since 2000 that will withstand the test of time