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In addition, studies have shown that p53 gene polymorphisms are associated with apoptotic signaling and smoking-related emphysema in smokers [149]

Expect a Break in Life Another reason you dream of smoking is that you want a break from the drudgery of life

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South African 'world's oldest man' wants to stop smoking Fredie Blom spent most of his life as a labourer - on a farm and in the construction industry - in apartheid South Africa but he might soon be recognised as the world's oldest man, as the BBC's Mohammed Allie reports from Cape Town