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Mecanismos secundarios documentados : Sntesis de matriz extracelular : estimula fibroblastos drmicos para producir colgeno I/III, elastina, glicosaminoglicanos (especialmente sulfato de dermatn) y proteoglicanos

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There were no significant differences in the proportions of no/low CKD risk or CKD patients achieving the more ambitious goal of a decrease of at least 2% in HbA1c and a loss of body weight of 10% or higher ( Figures 2C, D ), although this target was reached by a significantly lower proportion of patients diagnosed with very high CKD risk ( Figure 2D )

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