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This name is a nod to the comic book character, Wolverine

This gradual timeline is reflected in real clinical photos, where changes are documented at one month, three months, and six months after the final session

Transwell filter migration assays documented enhanced fibroblast migration

An important finding from animal studies: the minimally effective weight-based dosages determined in rats (2.5-5 ml per kg) are considerably higher than typical human clinical doses

Conventional thinking posits that a primary defect in adaptive immunity promotes recruitment and entry of peripherally activated lymphocytes into the CNS across a disrupted bloodbrain barrier where a complex cascade of autoimmune/inflammatory processes culminates in edema, and destruction of myelin, axons and oligodendrocytes (for detailed reviews see Dendrou et al., 2015

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