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In preliminary observations, abnormal mitotic spindles and DNA fragmentation of embryos was also observed, and Burruel et al

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Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction

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None of the included individuals had diagnosed liver or renal dysfunction at the time of sampling or were reported as malnourished