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The neurotransmitter glutamate has two major ionotropic receptors (NMDA and AMPA/kainate receptors), which are widespread in the cerebral cortex and other brain regions

Results: Out of 7,146,015 identified patients with T2DM, 10.3% were on a GLP-1 RA and 89.7% were not

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In one study, rats that were exposed to a lethal dose of acetaldehyde had very high survival rates after receiving L-cysteine

However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes

Its also believed to increase the aggregation of -synuclein, which is highly toxic to the neurons [6]