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The SURMOUNT-1 trial (Jastreboff et al., New England Journal of Medicine 2022) enrolled 2,539 adults with obesity and demonstrated 15% to 20.9% total body weight loss over 72 weeks
92,93 Subcutaneous administration of liraglutide (3 mg daily) and semaglutide (2.4 mg weekly) has been approved for obesity management
The GLP-1 mechanism Semaglutide belongs to the GLP-1 receptor agonist class of medications
The 9 mg and 12 mg doses tested in TRIUMPH-4 are expected to form the therapeutic range, with 2 mg as the starting dose
doi: 10.1038/ijo.2012.208 236 LockieSHHeppnerKMChaudharyNChabenneJRMorganDAVeyrat-DurebexCet al
By working closely with your healthcare provider and making lifestyle changes such as following a healthy diet and engaging in regular physical activity, you can optimize the effects of Trulicity on weight loss
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