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However, for an individual patient, the amount of weight modification needed to put the disease into remission varies, which raises a question of whether it is the type of adipose tissue or its location that is more relevant than the absolute amount of adipose tissue that is lost

et al: Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis

Maximum Weight Loss Potential (Future) Amycretin Subcutaneous amycretin achieved up to 24% weight loss at 36 weeks in phase 1b/2a, exceeding CagriSema's 20.4% at 68 weeks in phase 3

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In both our sites, we did see increased risks of developing these events, and both our studies do show statistical significance in terms of increased risk