One of the prominent mechanisms for tight junction regulation by astrocytes is by regulating the accumulation of agrin, a heparin sulfate proteoglycan which is important for BBB integrity in the basal lamina ( However, the exact mechanism whereby transcytosis may be affected by co-regulation between ECs, pericytes, and astrocytes is still unclear (Figure 1)
J Biol Chem 278 , 471478 (2003)
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Good levels of vitamin b12 in body relates to wellbeing of gut
It has been widely studied for applications in dermatology, regenerative medicine, and aging-related research for its role in tissue rejuvenation and healing 1-4