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Nevertheless, assessing effect size through meta-analysis was challenging due to significant heterogeneity among complex interventions across Cochrane reviews and clinical trials
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As biopsies are also not routinely performed to confirm the diagnosis of EVALI much like bronchoalveolar lavage, several studies have included them in the workup and revealed the most common histopathological findings to be diffuse alveolar damage, foamy macrophages, and interstitial pneumonitis [16]
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