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For optogenetic experiments on freely moving mice, an optical fiber (200 m core, NA = 0.39, Thor Labs) coupled to a ferule (1.25 mm) was implanted just above the VTA ipsilateral to the viral injection (coordinates from bregma: AP 3.1 mm, ML 0.5 mm, DV 4.4 mm from the skull), and fixed to the skull with dental cement (SuperBond, Sun Medical)

In the logistic regression analysis, the Op prevalence in PS was significantly higher compared to NS (Fig