The amount of pigmentation increases with greater tobacco use, and is more common in females
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As a consequence most victims are men too
[626] The USPSTF cautioned, [t]here is insufficient evidence about the potential harms of associated extracolonic findings, which are common. The USPSTF further wrote, [t]here are numerous screening tests to detect early-stage colorectal cancer, including stool-based tests (gFOBT, FIT, and FIT-DNA), direct visualization tests (flexible sigmoidoscopy, alone or combined with FIT