Risk of bias was assessed using the Cochrane Risk of Bias (ROB) tool for randomized controlled trials (RCTs) and the Risk of Bias Assessment Tool for Non-randomized Studies 2.0.7 For consistency, ROB 1.0 was used if applied in previous reviews, whereas the ROB 2.0 tool was used for de novo systematic reviews.8, 9 Two reviewers independently assessed each study, and any discrepancies were resolved through discussion
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Overall, out of the eight longitudinal and cross-sectional studies, only one found an increased cancer risk
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Companies certainly try to think throughsupported by analysis when possiblewhat they want to do, but they also have to adapt as they go along, whether because the thinking was faulty or because new ideas have come up, as unexpected problems have been solved or unforeseen opportunities encountered
With cannabis specifically, THC binds to fatty tissue and slowly re-enters oral fluid, which is why heavy daily use can show on a swab past 72 hours regardless of brushing