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Critical appraisal was conducted through detailed reading of the full text and focused on the following considerations: (1) possible violations of the correct temporal sequence, e.g., if respiratory symptoms or conditions could have been present from baseline and therefore co-occurred or preceded EC use

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In addition, water may ease certain discomforts that arise as a result of nicotine withdrawal (such as coughing, constipation and urge to eat)

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A few states and cities, however, have successfully taken matters into their own hands