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ACKNOWLEDGMENTS Preprint is available at REFERENCES 1

This was never the intent

The bowls I've smoked have all burned well, giving a cool smoke

Although still a relatively small problem, experts expect illicit trade in e-cigarettes will increase as demand grows

Snuff, intended for nasal use, but which Icelanders mostly take orally,[2] has been available since at least the 1940s,[3] and in recent years vapes and nicotine pouches have entered the market

To determine whether our observed pattern was universal across tissues, we also measured DNAm at our candidate Cyp1a1 position in offspring livers as primary site of Cyp1a1 expression