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Mayer found that the 60 mg dose would actually correspond to an oral LD50 (the amount of a poisonous substance required to kill 50% of those exposed) of around 0.8 mg/kg, or considerably less than the values determined for laboratory animals, which range from 3.3 (mice) to more than 50 mg/kg (rats)

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(1943) History of the Committee on Food Habits. In National Research Council, The Problem of Changing Food Habits: Report of the Committee on Food Habits 1941-1943, pp

This feels like a discreet way to lose weight." Zyn may suppress appetite short-term, but the collateral damage is huge Scientists suspect the reason nicotine works as a mild appetite suppressant is because it activates neurons in the brain that control hunger

Use it as a chance to strengthen your resolve to quit

When it was popular: Peaked in the late 1800s and early 1900s, decreased use in the mid 20th century when cigarettes took over the market, but still used today