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Its a good choice for the gut health benefits this supplement is designed to impart, as a pair of randomized, double-blind, and placebo-controlled trials in 2019 found that a 10g daily dose of the stuff significantly improved stool frequency in a cohort at increased risk for constipation (ages 4075).29 Other studies, including a 2024 systematic review and meta-analysis, determined that chicory inulin may even help with weight management.30 The issue is that successful studies have used very high doses at least 10g per day, as opposed to the 276mg in Akkermansia so the chicorys role here appears to be exclusively as a food for the bacterial species
However, we wont leave it at that
Medication may help create a window of opportunity, but sustainable habits still matter
Moreover, although the microbiome reached an adult-like stability at around 2 years of age, important taxonomic and functional changes did occur both before and after adolescence
The successful design, expression, and lab-scale process with substantial yield demonstrates suitability for early-stage development and future scalability
10.1038/cdd.2009.163 82 PetermannI.TriggsC
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