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While tirzepatide does not directly affect thyroid function, the caloric deficit it produces creates similar metabolic pressure

Configuration Required Selection Scientific Overview AOD9604 is a synthetic peptide analog derived from the C-terminal region (176191) of human growth hormone (HGH), consisting of a defined amino acid sequence produced through controlled peptide synthesis

5-Amino-1MQ and MOTS-c both reduced fat mass in rodent studies through NAD+-linked and AMPK-linked mechanisms [2][5]

We also observed increased expression of pro-inflammatory genes in both in vitro and ex vivo models of adipocytes

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All participants followed a calorie-restricted diet (~300 kcal/day deficit)