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Experimentally, cigarette smoke/cigarette smoke extract (CS/CSE) increases mitochondrial reactive oxygen species (mtROS), disrupts mitochondrial homeostasis, and promotes airway epithelial senescence 4

4 Much less is known about the adverse effects of longterm cigar or pipe smoking

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Please seek medical attention if someone is experiencing any severe symptoms after using cannabis or any drug

The nicotine content of the said smokeless tobacco product can gradually disrupt the natural balance of neurotransmitters, which then affects the brains ability to store and recall information properly