In order to detect a medium effect size of 0.625 (average accuracy increase of 0.08 and standard deviation of 0.128) for the primary outcome (MIFT accuracy), with an intra subject correlation of 0.3, a power of 80% a false positive rate set to 5%, and assuming a 30% dropout rate, the target sample size was 44 participants
Oxid Med Cell Longev (2022) 2022:9911167
Frei B: Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage
Villafuerte G et al
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However, a study in which volunteers were supplemented with N-acetylcysteine (NAC) and oral GSH 17 suggested that a sublingual form of glutathione may be beneficial