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These patients were then interviewed concerning smoking habits, as were controls selected from patients with other disorders (primarily, non-malignant) who were hospitalized in the same hospitals at the same time

One very important point: HTPs and e-cigarettes generally contain nicotine

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Response options included: You currently smoke (current smoking)

However, despite this absence of direct data, we might assume that most self-reported current smokers in Period 3 with a high cotinine level probably smoked regular cigarettes, whereas most self-reported former smokers with a high cotinine level had probably switched to e-cigarettes