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PTSD, major depression, and advanced transcriptomic age in brain tissue

We often have some data on a single peptide (or at least a plausible mechanism), but very little high-quality human evidence that stack A + stack B produces additive benefitor does so safely

Free Radic Biol Med 2009

5-Amino-1MQ operates as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme central to regulating nicotinamide metabolism and intracellular NAD+ levels

Myers believes: To make functional medicine more accessible, we as a society need to work on changing the perception of medicine as a whole

The problem is also predictable: most stacks have far more marketing momentum than clinical evidence, especially for combinations