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These products (gum, patches or lozenges sold over the counter, or nasal spray with a prescription) work by offering doses of nicotine that are absorbed more slowly to avoid the risk of addiction

the availability of illegal tobacco products, and the ultimately key factor relative levels of disadvantage, deprivation and poverty

Specifically, the BPRF framework uses a meta-regressionBayesian, regularized, trimmed (MR-BRT) tool to estimate pooled RRs, along with uncertainty intervals, accounting for systematic bias, within-study correlation and unexplained between-study heterogeneity

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