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Use of tobacco products causes many kinds of cancer Use of tobacco products is one of the most common risk factors for many types of cancers, including cancer of the lung, pancreas, mouth, throat, bladder, liver, stomach, colon, and nose to name a few

Side effects, drug interactions, dosage, and pregnancy safety information should be

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Cancer Epidemiol Biomarkers Prev 17(12): 3366-3371, 2008

The way I see it, a blend would seriously have to be down right nasty to not be enjoyed, if pipe smokers changed as many variables as Ive mentioned above