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This diverse community, which includes bacteria, viruses, fungi, and archaea, has co-evolved with humans over millennia, forming complex ecosystems that are essential for processes such as nutrient absorption, immune modulation, and pathogen defense [24,25,26]

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Begin using the gum on your quit day

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If you are outside, you can spit onto the ground, but if you are indoors, keep an empty water bottle to spit into