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You should not use Entonox if you have: A recent or current ear infection, or an operation on your ears Recent eye surgery where injections of gas have been used Recently been scuba diving (within 48 hours) or have decompression sickness A collapsed lung or pneumothorax Lung disease or breathing difficulties (unstable asthma, emphysema) A head injury (or suspected or known increased pressure on the brain) A known problem with air trapped in the body (e.g., in an artery) A severely bloated stomach Injuries to the face and jaw Paraquat poisoning (a weed killer) What are the side-effects of using Entonox