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Advances in mechanistic understanding have revealed a multifactorial pathogenesis, characterised by dysregulated inflammation, disruption of the gut-liver axis, oxidative stress, impaired regeneration, and genetic susceptibility, each of which offers rational targets for intervention

With respect to skeletal repair, it has been examined in models of bone injury and structural defects

Injectable forms have better bioavailability and more consistent absorption compared to oral versions

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In bodybuilding stacks, it may also be combined with anabolic agents, fat burners, or SARMs depending on cycle goals