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When these senses return to normal after quitting, food can become more enjoyable, leading to increased consumption

Withdrawal symptoms can include: Anxiety Depression Irritability Fatigue Intense drug cravings Withdrawal from cocaine is difficult and uncomfortable, which can make it hard to quit using the drug

In more modern times, gentlemen would smoke a pipe as a way to unwind and relax, or as a refined stimulation to intellectual pursuits like reading and writing

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Toxicol Lett 208:2329 Ginzkey C, Friehs G, Koehler C, Hackenberg S, Hagen R, Kleinsasser NH (2013) Assessment of nicotineinduced DNA damage in a genotoxicological test battery