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Those who said they would change their behavior noted that they would be willing to throw out their trash properly

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While chronic infections with HBV and HCV, heavy alcohol consumption, and diabetes are well-established primary risk factors for HCC, there is compelling and growing evidence that prolonged and active cigarette smoking is an independent and significant risk factor for its development [98, 99]

DSM-5 defined this condition as a problematic pattern of tobacco, resulting in clinically significant damage or distress, as demonstrated by at least two of the following, occurring within a 12-month period