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Serum Transaminases (AST/ALT) to establish baseline hepatic function

mean (SD) age ranged from 29.7 (11.0) to 40.8 (11.6) years, mean (SD) BMI ranged from 28.3 (3.4) to 33.9 (3.6) kg/m 2 , and the percentage of female participants ranged from 16.7% to 83.3% (Table 1)

Since none of the other models tested outperformed logistic regression, we used LightGBM to explore whether increasing the sample size would further improve either model

These metabolites can interact with cellular macromolecules, binding to DNA and proteins and forming adducts that disrupt normal cellular processes