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[199] The activated kinases then phosphorylate their respective transporter(s), which in turn causes a conformational change in transporter protein, thereby altering its function and affecting dopaminergic/glutamatergic neurotransmission at dopaminergic synapses

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a woman with low morals (derogatory) wanker - annoying person (derogatory) British Slang Phrases Before going deeper into your exploration of British slang words, take the time to discover some slang phrases commonly used in the U.K