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Insulin secretion rate was calculated by fitting C-peptide concentrations at each time point during the OGTT to an established model of C-peptide deconvolution 26,27,28

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Pancreas-related risks: a) Acute Pancreatitis: There have been reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, in patients treated with GLP-1 receptor agonists